| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine kinase |
|---|
| Ligand | BDBM50134740 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31113 (CHEMBL642224) |
|---|
| IC50 | 0.47±n/a nM |
|---|
| Citation |  Ugarkar, BG; Castellino, AJ; DaRe, JS; Ramirez-Weinhouse, M; Kopcho, JJ; Rosengren, S; Erion, MD Adenosine kinase inhibitors. 3. Synthesis, SAR, and antiinflammatory activity of a series of l-lyxofuranosyl nucleosides. J Med Chem46:4750-60 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine kinase |
|---|
| Name: | Adenosine kinase |
|---|
| Synonyms: | ADK | ADK_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40545.97 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1467841 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
|
|
|
|---|
| BDBM50134740 |
|---|
| n/a |
|---|
| Name | BDBM50134740 |
|---|
| Synonyms: | (1R,4S,5R)-2-Hydroxymethyl-5-(5-phenyl-4-phenylamino-pyrrolo[2,3-d]pyrimidin-7-yl)-tetrahydro-furan-3,4-diol | (2R,3R,4S,5S)-2-Hydroxymethyl-5-(5-phenyl-4-phenylamino-pyrrolo[2,3-d]pyrimidin-7-yl)-tetrahydro-furan-3,4-diol | CHEMBL343247 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H22N4O4 |
|---|
| Mol. Mass. | 418.4452 |
|---|
| SMILES | OC[C@@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(-c2ccccc2)c2c(Nc3ccccc3)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
