| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor alpha |
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| Ligand | BDBM28700 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153713 (CHEMBL759644) |
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| EC50 | 131300±n/a nM |
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| Citation |  Sauerberg, P; Bury, PS; Mogensen, JP; Deussen, HJ; Pettersson, I; Fleckner, J; Nehlin, J; Frederiksen, KS; Albrektsen, T; Din, N; Svensson, LA; Ynddal, L; Wulff, EM; Jeppesen, L Large dimeric ligands with favorable pharmacokinetic properties and peroxisome proliferator-activated receptor agonist activity in vitro and in vivo. J Med Chem46:4883-94 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor alpha |
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| Name: | Peroxisome proliferator-activated receptor alpha |
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| Synonyms: | Nr1c1 | Nuclear receptor subfamily 1 group C member 1 | PPAR-alpha | PPARA_RAT | Peroxisome Proliferator-Activated Receptor alpha | Ppar | Ppara |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52374.28 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_834194 |
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| Residue: | 468 |
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| Sequence: | MVDTESPICPLSPLEADDLESPLSEEFLQEMGNIQEISQSLGEESSGSFSFADYQYLGSC
PGSEGSVITDTLSPASSPSSVSCPAVPTSTDESPGNALNIECRICGDKASGYHYGVHACE
GCKGFFRRTIRLKLAYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSE
KAKLKAEILTCEHDLKDSETADLKSLAKRIHEAYLKNFNMNKVKARVILAGKTSNNPPFV
IHDMETLCMAEKTLVAKMVANGVENKEAEVRFFHCCQCMSVETVTELTEFAKAIPGFANL
DLNDQVTLLKYGVYEAIFTMLSSLMNKDGMLIAYGNGFITREFLKNLRKPFCDIMEPKFD
FAMKFNALELDDSDISLFVAAIICCGDRPGLLNIGYIEKLQEGIVHVLKLHLQSNHPDDT
FLFPKLLQKMVDLRQLVTEHAQLVQVIKKTESDAALHPLLQEIYRDMY
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| BDBM28700 |
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| n/a |
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| Name | BDBM28700 |
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| Synonyms: | 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid | 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid | CHEMBL981 | FENOFIBRIC ACID | FIBRICOR | Fenofibrate | LF 153 | alpha-1081 | procetofenic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15ClO4 |
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| Mol. Mass. | 318.752 |
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| SMILES | CC(C)(Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1)C(O)=O |
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| Structure | 
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