| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50135288 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196715 |
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| Ki | 180±n/a nM |
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| Citation |  Kitade, Y; Kojima, H; Zulfiqur, F; Kim, HS; Wataya, Y Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. Bioorg Med Chem Lett13:3963-5 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AdoHcyase | PfSAHH | S-adenosyl-L-homocysteine hydrolase | SAHH_PLAF7 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53833.80 |
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| Organism: | Plasmodium falciparum 3D7 |
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| Description: | ChEMBL_196715 |
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| Residue: | 479 |
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| Sequence: | MVENKSKVKDISLAPFGKMQMEISENEMPGLMRIREEYGKDQPLKNAKITGCLHMTVECA
LLIETLQKLGAQIRWCSCNIYSTADYAAAAVSTLENVTVFAWKNETLEEYWWCVESALTW
GDGDDNGPDMIVDDGGDATLLVHKGVEYEKLYEEKNILPDPEKAKNEEERCFLTLLKNSI
LKNPKKWTNIAKKIIGVSEETTTGVLRLKKMDKQNELLFTAINVNDAVTKQKYDNVYGCR
HSLPDGLMRATDFLISGKIVVICGYGDVGKGCASSMKGLGARVYITEIDPICAIQAVMEG
FNVVTLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNELFNYKG
IHIENVKPQVDRITLPNGNKIIVLARGRLLNLGCATGHPAFVMSFSFCNQTFAQLDLWQN
KDTNKYENKVYLLPKHLDEKVALYHLKKLNASLTELDDNQCQFLGVNKSGPFKSNEYRY
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| BDBM50135288 |
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| n/a |
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| Name | BDBM50135288 |
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| Synonyms: | (1S,2R,3S,4R)-4-(6-Amino-purin-9-yl)-cyclopentane-1,2,3-triol | (1S,2R,3S,4R)-4-(6-amino-9H-purin-9-yl)cyclopentane-1,2,3-triol | CHEMBL129014 | NORARISTEROMYCIN |
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| Type | Small organic molecule |
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| Emp. Form. | C10H13N5O3 |
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| Mol. Mass. | 251.2419 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O |
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| Structure | 
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