Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCarboxypeptidase M
LigandBDBM50135937
Substrate/Competitorn/a
Meas. Tech.ChEMBL_45790
IC50>50000±n/a nM
Citation Barrow JCNantermet PGStauffer SRNgo PLSteinbeiser MAMao SSCarroll SSBailey CColussi DBosserman MBurlein CCook JJSitko GTiller PRMiller-Stein CMRose MMcMasters DRVacca JPSelnick HG Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithrombotics. J Med Chem 46:5294-7 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carboxypeptidase M
Name:Carboxypeptidase M
Synonyms:CPM
Type:PROTEIN
Mol. Mass.:50519.81
Organism:Homo sapiens (Human)
Description:ChEMBL_45790
Residue:443
Sequence:
MDFPCLWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVL
VVGRFPKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIH
IMPSMNPDGFEAVKKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSRQPETVAVMKWLKT
ETFVLSANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD
ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNN
KASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSY
IINVTVPGHDPHITKVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNLP
DHSAATKPSLFLFLVSLLHIFFK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50135937
n/a
NameBDBM50135937
Synonyms:3-(6-Amino-pyridin-3-yl)-2-(1-methyl-1H-imidazol-4-yl)-propionic acid | CHEMBL344949
TypeSmall organic molecule
Emp. Form.C12H14N4O2
Mol. Mass.246.2652
SMILESCn1cnc(c1)C(Cc1ccc(N)nc1)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: