| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
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| Ligand | BDBM50136400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105266 |
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| Ki | 0.400000±n/a nM |
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| Citation |  Sun, LQ; Chen, J; Mattson, RJ; Epperson, JR; Deskus, JA; Li, WS; Takaki, K; Hodges, DB; Iben, L; Mahle, CD; Ortiz, A; Molstad, D; Ryan, E; Yeleswaram, K; Xu, C; Luo, G Heterocyclic aminopyrrolidine derivatives as melatoninergic agents. Bioorg Med Chem Lett13:4381-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1B |
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| Name: | Melatonin receptor type 1B |
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| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50136400 |
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| n/a |
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| Name | BDBM50136400 |
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| Synonyms: | CHEMBL343825 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-3-yl]-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O2 |
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| Mol. Mass. | 260.3315 |
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| SMILES | CCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12 |
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| Structure | 
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