| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50136405 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105102 |
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| Ki | 0.900000±n/a nM |
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| Citation |  Sun, LQ; Chen, J; Mattson, RJ; Epperson, JR; Deskus, JA; Li, WS; Takaki, K; Hodges, DB; Iben, L; Mahle, CD; Ortiz, A; Molstad, D; Ryan, E; Yeleswaram, K; Xu, C; Luo, G Heterocyclic aminopyrrolidine derivatives as melatoninergic agents. Bioorg Med Chem Lett13:4381-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50136405 |
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| n/a |
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| Name | BDBM50136405 |
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| Synonyms: | 1-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-3-yl]-3-methyl-urea | CHEMBL138012 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N3O2 |
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| Mol. Mass. | 261.3196 |
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| SMILES | CNC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12 |
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| Structure | 
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