| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50136722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_99665 (CHEMBL705073) |
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| IC50 | 1100±n/a nM |
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| Citation |  McKew, JC; Lovering, F; Clark, JD; Bemis, J; Xiang, Y; Shen, M; Zhang, W; Alvarez, JC; Joseph-McCarthy, D Structure-activity relationships of indole cytosolic phospholipase A(2)alpha inhibitors: substrate mimetics. Bioorg Med Chem Lett13:4501-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50136722 |
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| n/a |
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| Name | BDBM50136722 |
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| Synonyms: | 4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid | CHEMBL140539 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H24BrNO3 |
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| Mol. Mass. | 526.42 |
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| SMILES | COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12)C(O)=O |
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| Structure | 
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