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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 2 | ||
| Ligand | BDBM50137265 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_160557 (CHEMBL763144) | ||
| IC50 | 17.0±n/a nM | ||
| Citation |  Parmee, ER; He, J; Mastracchio, A; Edmondson, SD; Colwell, L; Eiermann, G; Feeney, WP; Habulihaz, B; He, H; Kilburn, R; Leiting, B; Lyons, K; Marsilio, F; Patel, RA; Petrov, A; Di Salvo, J; Wu, JK; Thornberry, NA; Weber, AE 4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett14:43-6 (2003) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 2 | |||
| Name: | Dipeptidyl peptidase 2 | ||
| Synonyms: | DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase | ||
| Type: | Protein | ||
| Mol. Mass.: | 54339.29 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9UHL4 | ||
| Residue: | 492 | ||
| Sequence: |
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| BDBM50137265 | |||
| n/a | |||
| Name | BDBM50137265 | ||
| Synonyms: | 1-[4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-3-(3,4-dichloro-phenyl)-urea | CHEMBL3084954 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H24Cl2N4O2S | ||
| Mol. Mass. | 431.38 | ||
| SMILES | [H][C@@]1(CC[C@@H](CC1)NC(=O)Nc1ccc(Cl)c(Cl)c1)[C@H](N)C(=O)N1CCSC1 |wU:4.7,1.0,wD:19.21,(1.73,2.3,;3.06,1.54,;1.75,.76,;1.75,-.78,;3.06,-1.54,;4.39,-.78,;4.39,.76,;3.06,-3.08,;4.41,-3.85,;5.74,-3.08,;4.41,-5.39,;5.74,-6.16,;7.07,-5.39,;8.4,-6.14,;8.41,-7.7,;9.74,-8.47,;7.07,-8.47,;7.07,-10.01,;5.74,-7.7,;3.06,3.08,;1.73,3.85,;4.41,3.87,;4.41,5.41,;5.74,3.08,;7.15,3.71,;8.17,2.57,;7.4,1.23,;5.9,1.56,)| | ||
| Structure | 
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