| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Matrix metalloproteinase-26 |
|---|
| Ligand | BDBM50137276 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_104566 |
|---|
| IC50 | 86.0±n/a nM |
|---|
| Citation |  Ma, D; Wu, W; Yang, G; Li, J; Li, J; Ye, Q Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett14:47-50 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Matrix metalloproteinase-26 |
|---|
| Name: | Matrix metalloproteinase-26 |
|---|
| Synonyms: | Endometase | MMP-26 | MMP26 | MMP26_HUMAN | Matrilysin-2 | Matrix metalloproteinase 26 | Matrix metalloproteinase-26 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 29707.55 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_806653 |
|---|
| Residue: | 261 |
|---|
| Sequence: | MQLVILRVTIFLPWCFAVPVPPAADHKGWDFVEGYFHQFFLTKKESPLLTQETQTQLLQQ
FHRNGTDLLDMQMHALLHQPHCGVPDGSDTSISPGRCKWNKHTLTYRIINYPHDMKPSAV
KDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAHEDGWPFDGPGGILGHAFLPNSG
NPGVVHFDKNEHWSASDTGYNLFLVATHEIGHSLGLQHSGNQSSIMYPTYWYHDPRTFQL
SADDIQRIQHLYGEKCSSDIP
|
|
|
|---|
| BDBM50137276 |
|---|
| n/a |
|---|
| Name | BDBM50137276 |
|---|
| Synonyms: | 6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | CHEMBL148214 | N,6-dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H20N2O7S |
|---|
| Mol. Mass. | 408.426 |
|---|
| SMILES | COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)c(OC)cc2C1C(=O)NO |
|---|
| Structure | 
|
|---|
Search and Browse
