| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM50137276 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105059 |
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| IC50 | 3192±n/a nM |
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| Citation |  Ma, D; Wu, W; Yang, G; Li, J; Li, J; Ye, Q Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors. Bioorg Med Chem Lett14:47-50 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM50137276 |
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| n/a |
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| Name | BDBM50137276 |
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| Synonyms: | 6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide | CHEMBL148214 | N,6-dihydroxy-7-methoxy-2-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N2O7S |
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| Mol. Mass. | 408.426 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N1CCc2cc(O)c(OC)cc2C1C(=O)NO |
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| Structure | 
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