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TargetReplication protein E1
LigandBDBM50137882
Substrate/Competitorn/a
Meas. Tech.ChEBML_84985
IC50 3300±n/a nM
Citation Faucher AMWhite PWBrochu CGrand-Maître CRancourt JFazal G Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase. J Med Chem 47:18-21 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Replication protein E1
Name:Replication protein E1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:73515.58
Organism:Human papillomavirus type 11
Description:ChEMBL_84985
Residue:649
Sequence:
MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNS
VEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPK
KVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAE
AVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVA
GFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLN
IPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHSLADSQFKLTE
MVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVKDCAIMCRHYKHAEMKK
MSIKQWIKYRGTKVDSVGNWKPIVQFLRHQNIEFIPFLSKLKLWLHGTPKKNCIAIVGPP
DTGKSCFCMSLIKFLGGTVISYVNSCSHFWLQPLTDAKVALLDDATQPCWTYMDTYMRNL
LDGNPMSIDRKHRALTLIKCPPLLVTSNIDISKEEKYKYLHSRVTTFTFPNPFPFDRNGN
AVYELSDANWKCFFERLSSSLDIEDSEDEEDGSNSQAFRCVPGSVVRTL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50137882
n/a
NameBDBM50137882
Synonyms:CHEMBL368466 | [4'-(Piperidine-1-carbonyl)-biphenyl-4-sulfonyl]-acetic acid
TypeSmall organic molecule
Emp. Form.C20H21NO5S
Mol. Mass.387.449
SMILESOC(=O)CS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C(=O)N1CCCCC1
Structure
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