| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Replication protein E1 |
|---|
| Ligand | BDBM50137886 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_84985 |
|---|
| IC50 | 320±n/a nM |
|---|
| Citation |  Faucher AM; White PW; Brochu C; Grand-Maître C; Rancourt J; Fazal G Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase. J Med Chem 47:18-21 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Replication protein E1 |
|---|
| Name: | Replication protein E1 |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 73515.58 |
|---|
| Organism: | Human papillomavirus type 11 |
|---|
| Description: | ChEMBL_84985 |
|---|
| Residue: | 649 |
|---|
| Sequence: | MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNS
VEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPK
KVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAE
AVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVA
GFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLN
IPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHSLADSQFKLTE
MVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVKDCAIMCRHYKHAEMKK
MSIKQWIKYRGTKVDSVGNWKPIVQFLRHQNIEFIPFLSKLKLWLHGTPKKNCIAIVGPP
DTGKSCFCMSLIKFLGGTVISYVNSCSHFWLQPLTDAKVALLDDATQPCWTYMDTYMRNL
LDGNPMSIDRKHRALTLIKCPPLLVTSNIDISKEEKYKYLHSRVTTFTFPNPFPFDRNGN
AVYELSDANWKCFFERLSSSLDIEDSEDEEDGSNSQAFRCVPGSVVRTL
|
|
|
|---|
| BDBM50137886 |
|---|
| n/a |
|---|
| Name | BDBM50137886 |
|---|
| Synonyms: | CHEMBL175036 | {3'-[((R)-1-Phenyl-ethylcarbamoyl)-methyl]-biphenyl-4-sulfonyl}-acetic acid | {3'-[(1-(R)-Phenyl-ethylcarbamoyl)-methyl]-biphenyl-4-sulfonyl}-acetic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H23NO5S |
|---|
| Mol. Mass. | 437.508 |
|---|
| SMILES | C[C@@H](NC(=O)Cc1cccc(c1)-c1ccc(cc1)S(=O)(=O)CC(O)=O)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
