| Reaction Details |
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 | Report a problem with these data |
| Target | Replication protein E1 |
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| Ligand | BDBM50137885 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_84985 |
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| IC50 | >80000±n/a nM |
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| Citation |  Faucher AM; White PW; Brochu C; Grand-Maître C; Rancourt J; Fazal G Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase. J Med Chem 47:18-21 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Replication protein E1 |
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| Name: | Replication protein E1 |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73515.58 |
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| Organism: | Human papillomavirus type 11 |
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| Description: | ChEMBL_84985 |
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| Residue: | 649 |
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| Sequence: | MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNS
VEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPK
KVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAE
AVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVA
GFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLN
IPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHSLADSQFKLTE
MVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVKDCAIMCRHYKHAEMKK
MSIKQWIKYRGTKVDSVGNWKPIVQFLRHQNIEFIPFLSKLKLWLHGTPKKNCIAIVGPP
DTGKSCFCMSLIKFLGGTVISYVNSCSHFWLQPLTDAKVALLDDATQPCWTYMDTYMRNL
LDGNPMSIDRKHRALTLIKCPPLLVTSNIDISKEEKYKYLHSRVTTFTFPNPFPFDRNGN
AVYELSDANWKCFFERLSSSLDIEDSEDEEDGSNSQAFRCVPGSVVRTL
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| BDBM50137885 |
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| n/a |
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| Name | BDBM50137885 |
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| Synonyms: | 2-(Biphenyl-4-sulfonyl)-2-methyl-propionic acid | CHEMBL366763 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16O4S |
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| Mol. Mass. | 304.361 |
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| SMILES | CC(C)(C(O)=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 |
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| Structure | 
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