| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Replication protein E1 |
|---|
| Ligand | BDBM50137895 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_84985 |
|---|
| IC50 | 630±n/a nM |
|---|
| Citation |  Faucher, AM; White, PW; Brochu, C; Grand-Maître, C; Rancourt, J; Fazal, G Discovery of small-molecule inhibitors of the ATPase activity of human papillomavirus E1 helicase. J Med Chem47:18-21 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Replication protein E1 |
|---|
| Name: | Replication protein E1 |
|---|
| Synonyms: | E1 | VE1_HPV11 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 73515.58 |
|---|
| Organism: | Human papillomavirus type 11 |
|---|
| Description: | ChEMBL_84985 |
|---|
| Residue: | 649 |
|---|
| Sequence: | MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNS
VEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPK
KVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAE
AVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVA
GFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLN
IPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHSLADSQFKLTE
MVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVKDCAIMCRHYKHAEMKK
MSIKQWIKYRGTKVDSVGNWKPIVQFLRHQNIEFIPFLSKLKLWLHGTPKKNCIAIVGPP
DTGKSCFCMSLIKFLGGTVISYVNSCSHFWLQPLTDAKVALLDDATQPCWTYMDTYMRNL
LDGNPMSIDRKHRALTLIKCPPLLVTSNIDISKEEKYKYLHSRVTTFTFPNPFPFDRNGN
AVYELSDANWKCFFERLSSSLDIEDSEDEEDGSNSQAFRCVPGSVVRTL
|
|
|
|---|
| BDBM50137895 |
|---|
| n/a |
|---|
| Name | BDBM50137895 |
|---|
| Synonyms: | 4'-Nitromethanesulfonyl-biphenyl-3-carboxylic acid (naphthalen-1-ylmethyl)-amide | 4-Nitromethanesulfonyl-biphenyl-3-carboxylic acid (naphthalene-1-ylmethyl)-amide | CHEMBL366836 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H20N2O5S |
|---|
| Mol. Mass. | 460.502 |
|---|
| SMILES | [O-][N+](=O)CS(=O)(=O)c1ccc(cc1)-c1cccc(c1)C(=O)NCc1cccc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
