| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50135800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_145149 (CHEMBL755953) |
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| Ki | 0.06±n/a nM |
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| Citation |  Zhang, A; Xiong, W; Bidlack, JM; Hilbert, JE; Knapp, BI; Wentland, MP; Neumeyer, JL 10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors. J Med Chem47:165-74 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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| BDBM50135800 |
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| n/a |
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| Name | BDBM50135800 |
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| Synonyms: | (-)-3-Hydroxy-N-cycloproypylmethylmorphinan Mandelate | 17-cyclopropylmethyl-(1R,9R,10R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol | 3-Hydroxy-N-cyclopropylmethylmorphinan | CHEMBL49269 | CYCLORPHAN | US10231963, Table B.6 | US10736890, Compound TABLE B.6 | US11534436, Compound Table B.6 | US9656961, Example 00123 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27NO |
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| Mol. Mass. | 297.4345 |
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| SMILES | Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC3CC3)c2c1 |
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| Structure | 
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