| Reaction Details |
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 | Report a problem with these data |
| Target | Plasminogen |
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| Ligand | BDBM50138675 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155235 (CHEMBL764725) |
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| Ki | 1970±n/a nM |
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| Citation |  Wendt, MD; Rockway, TW; Geyer, A; McClellan, W; Weitzberg, M; Zhao, X; Mantei, R; Nienaber, VL; Stewart, K; Klinghofer, V; Giranda, VL Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution. J Med Chem47:303-24 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasminogen |
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| Name: | Plasminogen |
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| Synonyms: | Activation peptide | Angiostatin | PLG | PLMN_HUMAN | Plasmin | Plasmin heavy chain A | Plasmin heavy chain A, short form | Plasmin light chain B |
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| Type: | Enzyme |
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| Mol. Mass.: | 90579.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 810 |
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| Sequence: | MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
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| BDBM50138675 |
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| n/a |
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| Name | BDBM50138675 |
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| Synonyms: | 6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-carbamoyl-phenyl)-amide | CHEMBL320749 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16N4O2 |
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| Mol. Mass. | 332.3559 |
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| SMILES | NC(=N)c1ccc2cc(ccc2c1)C(=O)Nc1ccc(cc1)C(N)=O |
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| Structure | 
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