| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1A |
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| Ligand | BDBM50139354 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_912 |
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| Ki | 41±n/a nM |
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| Citation |  Thomson, CG; Beer, MS; Curtis, NR; Diggle, HJ; Handford, E; Kulagowski, JJ Thiazoles and thiopyridines: novel series of high affinity h5HT(7) ligands. Bioorg Med Chem Lett14:677-80 (2004) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1A |
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| Name: | 5-hydroxytryptamine receptor 1A |
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| Synonyms: | 5-HT-1A | 5-HT1A | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | Dopamine D2 receptor and serotonin 1a receptor | G-21 | HTR1A | Serotonin receptor 1A |
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| Type: | n/a |
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| Mol. Mass.: | 46122.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 422 |
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| Sequence: | MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT
RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
RQ
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| BDBM50139354 |
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| n/a |
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| Name | BDBM50139354 |
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| Synonyms: | 1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]-cyclohexanol | CHEMBL159143 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H24N2OS |
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| Mol. Mass. | 280.429 |
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| SMILES | CN(C)CCSc1cccc(n1)C1(O)CCCCC1 |
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| Structure | 
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