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TargetCannabinoid receptor 1
LigandBDBM50140226
Substrate/Competitorn/a
Meas. Tech.ChEBML_46467
Ki 94±n/a nM
Citation Dyck BGoodfellow VSPhillips TGrey JHaddach MRowbottom MNaeve GSBrown BSaunders J Potent imidazole and triazole CB1 receptor antagonists related to SR141716. Bioorg Med Chem Lett 14:1151-4 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1
Name:Cannabinoid receptor 1
Synonyms:CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52868.96
Organism:Homo sapiens (Human)
Description:P21554
Residue:472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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  Blast E-value cutoff:
BDBM50140226
n/a
NameBDBM50140226
Synonyms:1-(4-Chloro-phenyl)-5-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid (4-methyl-cyclohexyl)-amide | CHEMBL15772
TypeSmall organic molecule
Emp. Form.C22H21Cl3N4O
Mol. Mass.463.787
SMILESCC1CCC(CC1)NC(=O)c1nc(-c2ccc(Cl)cc2Cl)n(n1)-c1ccc(Cl)cc1 |(7.1,3.77,;5.63,3.3,;4.49,4.32,;3.03,3.86,;2.71,2.34,;3.85,1.32,;5.31,1.79,;1.26,1.88,;.12,2.89,;.43,4.39,;-1.37,2.41,;-2.61,3.32,;-3.86,2.41,;-5.32,2.89,;-6.46,1.85,;-7.93,2.32,;-8.26,3.83,;-9.75,4.25,;-7.11,4.86,;-5.65,4.39,;-4.55,5.49,;-3.39,.93,;-1.84,.93,;-4.3,-.31,;-3.67,-1.71,;-4.56,-2.96,;-6.11,-2.8,;-6.89,-4.13,;-6.74,-1.38,;-5.83,-.14,)|
Structure
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