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TargetCannabinoid receptor 1
LigandBDBM50140228
Substrate/Competitorn/a
Meas. Tech.ChEBML_46467
Ki 164±n/a nM
Citation Dyck BGoodfellow VSPhillips TGrey JHaddach MRowbottom MNaeve GSBrown BSaunders J Potent imidazole and triazole CB1 receptor antagonists related to SR141716. Bioorg Med Chem Lett 14:1151-4 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1
Name:Cannabinoid receptor 1
Synonyms:CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52868.96
Organism:Homo sapiens (Human)
Description:P21554
Residue:472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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  Blast E-value cutoff:
BDBM50140228
n/a
NameBDBM50140228
Synonyms:5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid (hexahydro-cyclopenta[c]pyrrol-2-yl)-amide | CHEMBL15877
TypeSmall organic molecule
Emp. Form.C22H20Cl3N5O
Mol. Mass.476.786
SMILESClc1ccc(cc1)-c1nc(nn1-c1ccc(Cl)cc1Cl)C(=O)NN1CC2CCCC2C1
Structure
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