| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50140311 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_105100 |
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| Ki | 4.9±n/a nM |
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| Citation |  Sun, LQ; Chen, J; Takaki, K; Johnson, G; Iben, L; Mahle, CD; Ryan, E; Xu, C Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands. Bioorg Med Chem Lett14:1197-200 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50140311 |
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| n/a |
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| Name | BDBM50140311 |
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| Synonyms: | CHEMBL19050 | N-[(1R,2R)-2-(2-Propyl-2,3-dihydro-benzooxazol-7-yl)-cyclopropylmethyl]-isobutyramide |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N2O2 |
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| Mol. Mass. | 302.4112 |
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| SMILES | CCCC1Nc2cccc([C@@H]3C[C@H]3CNC(=O)C(C)C)c2O1 |
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| Structure | 
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