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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dipeptidyl peptidase 2 | ||
| Ligand | BDBM50140523 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_160555 | ||
| IC50 | 690±n/a nM | ||
| Citation |  Caldwell, CG; Chen, P; He, J; Parmee, ER; Leiting, B; Marsilio, F; Patel, RA; Wu, JK; Eiermann, GJ; Petrov, A; He, H; Lyons, KA; Thornberry, NA; Weber, AE Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors. Bioorg Med Chem Lett14:1265-8 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dipeptidyl peptidase 2 | |||
| Name: | Dipeptidyl peptidase 2 | ||
| Synonyms: | DAP II | DPP2 | DPP2_HUMAN | DPP7 | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP II) | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | Dipeptidyl peptidase II (DPP2) | Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4) | QPP | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase | ||
| Type: | Protein | ||
| Mol. Mass.: | 54339.29 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q9UHL4 | ||
| Residue: | 492 | ||
| Sequence: |
| ||
| BDBM50140523 | |||
| n/a | |||
| Name | BDBM50140523 | ||
| Synonyms: | CHEMBL22359 | N-[4-((S)-1-Amino-2-oxo-2-thiazolidin-3-yl-ethyl)-cyclohexyl]-3,4-difluoro-benzamide | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H23F2N3O2S | ||
| Mol. Mass. | 383.456 | ||
| SMILES | N[C@@H]([C@H]1CC[C@@H](CC1)NC(=O)c1ccc(F)c(F)c1)C(=O)N1CCSC1 |wU:5.8,1.0,wD:2.2,(3.41,-2.93,;3.41,-1.4,;2.09,-.63,;2.09,.91,;.75,1.67,;-.57,.91,;-.57,-.63,;.75,-1.4,;-1.9,1.69,;-3.23,.93,;-3.23,-.61,;-4.57,1.69,;-5.89,.93,;-7.24,1.69,;-7.24,3.24,;-8.57,4.01,;-5.89,4.01,;-5.87,5.54,;-4.57,3.24,;4.74,-.63,;4.74,.91,;6.07,-1.4,;7.39,-.63,;8.54,-1.67,;7.9,-3.05,;6.39,-2.9,)| | ||
| Structure | 
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