| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
|---|
| Ligand | BDBM50141594 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_196588 |
|---|
| Ki | 2700±n/a nM |
|---|
| Citation |  Michellys, PY; D'Arrigo, J; Grese, TA; Karanewsky, DS; Leibowitz, MD; Mais, DA; Mapes, CM; Reifel-Miller, A; Rungta, D; Boehm, MF Design, synthesis and structure-activity relationship of novel RXR-selective modulators. Bioorg Med Chem Lett14:1593-8 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-beta |
|---|
| Name: | Retinoic acid receptor RXR-beta |
|---|
| Synonyms: | Nr2b2 | RXRB_MOUSE | Retinoid X receptor beta | Rxrb |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 55877.78 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_196588 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
|
|
|
|---|
| BDBM50141594 |
|---|
| n/a |
|---|
| Name | BDBM50141594 |
|---|
| Synonyms: | (E)-3-{7-[3,5-Diisopropyl-2-(2,2,2-trifluoro-ethoxy)-phenyl]-benzofuran-2-yl}-but-2-enoic acid | CHEMBL39206 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H27F3O4 |
|---|
| Mol. Mass. | 460.4854 |
|---|
| SMILES | CC(C)c1cc(C(C)C)c(OCC(F)(F)F)c(c1)-c1cccc2cc(oc12)C(\C)=C\C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
