| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-gamma |
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| Ligand | BDBM50129720 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_196589 |
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| Ki | >1000±n/a nM |
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| Citation |  Michellys, PY; D'Arrigo, J; Grese, TA; Karanewsky, DS; Leibowitz, MD; Mais, DA; Mapes, CM; Reifel-Miller, A; Rungta, D; Boehm, MF Design, synthesis and structure-activity relationship of novel RXR-selective modulators. Bioorg Med Chem Lett14:1593-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor RXR-gamma |
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| Name: | Retinoic acid receptor RXR-gamma |
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| Synonyms: | Nr2b3 | RXRG_MOUSE | Retinoid X receptor gamma | Rxrg |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50900.28 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_196589 |
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| Residue: | 463 |
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| Sequence: | MYGNYSHFMKFPTGFGGSPGHTGSTSMSPSVALPTGKPMDSHPSYTDTPVSAPRTLSAVG
TPLNALGSPYRVITSAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG
IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKD
CLIDKRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAECASSSHEDMPVERIL
EAELAVEPKTESYGDMNVENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVI
LLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD
MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLL
LRLPALRSIGLKCLEHLFFFKLIGDTPIDSFLMEMLETPLQIT
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| BDBM50129720 |
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| n/a |
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| Name | BDBM50129720 |
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| Synonyms: | (2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-3-methyl-octa-2,4,6-trienoic acid | 7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-3-methyl-octa-2,4,6-trienoic acid | CHEMBL42314 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34F2O3 |
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| Mol. Mass. | 420.5325 |
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| SMILES | C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O |
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| Structure | 
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