| Reaction Details |
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 | Report a problem with these data |
| Target | Plasminogen |
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| Ligand | BDBM50142161 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155053 |
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| IC50 | >11000±n/a nM |
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| Citation |  Zhang, P; Bao, L; Zuckett, JF; Jia, ZJ; Woolfrey, J; Arfsten, A; Edwards, S; Sinha, U; Hutchaleelaha, A; Lambing, JL; Hollenbach, SJ; Scarborough, RM; Zhu, BY Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity. Bioorg Med Chem Lett14:989-93 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasminogen |
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| Name: | Plasminogen |
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| Synonyms: | Activation peptide | Angiostatin | PLG | PLMN_HUMAN | Plasmin | Plasmin heavy chain A | Plasmin heavy chain A, short form | Plasmin light chain B |
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| Type: | Enzyme |
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| Mol. Mass.: | 90579.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 810 |
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| Sequence: | MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECAAKCEEDEEFT
CRAFQYHSKEQQCVIMAENRKSSIIIRMRDVVLFEKKVYLSECKTGNGKNYRGTMSKTKN
GITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILE
CEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPDRE
LRPWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWS
AQTPHTHNRTPENFPCKNLDENYCRNPDGKRAPWCHTTNSQVRWEYCKIPSCDSSPVSTE
QLAPTAPPELTPVVQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAG
LTMNYCRNPDADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEED
CMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVGG
PWCYTTNPRKLYDYCDVPQCAAPSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRT
RFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLE
PTRKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLKEAQ
LPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW
GLGCARPNKPGVYVRVSRFVTWIEGVMRNN
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| BDBM50142161 |
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| n/a |
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| Name | BDBM50142161 |
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| Synonyms: | 5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-{[methyl-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-amino]-methyl}-benzoylamino)-benzamide | CHEMBL175130 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24Cl2N6O2 |
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| Mol. Mass. | 511.403 |
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| SMILES | CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C1=NCCN1C |t:32| |
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| Structure | 
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