| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine kinase |
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| Ligand | BDBM50143574 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_31117 |
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| IC50 | 1±n/a nM |
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| Citation |  Bauser, M; Delapierre, G; Hauswald, M; Flessner, T; D'Urso, D; Hermann, A; Beyreuther, B; De Vry, J; Spreyer, P; Reissmüller, E; Meier, H Discovery and optimization of 2-aryl oxazolo-pyrimidines as adenosine kinase inhibitors using liquid phase parallel synthesis. Bioorg Med Chem Lett14:1997-2000 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine kinase |
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| Name: | Adenosine kinase |
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| Synonyms: | ADK | ADK_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40545.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1467841 |
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| Residue: | 362 |
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| Sequence: | MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAED
KHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKA
AEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKAR
VCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGN
ETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFA
VLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPD
FH
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| BDBM50143574 |
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| n/a |
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| Name | BDBM50143574 |
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| Synonyms: | 7-((4aS,7aS)-6-Benzyl-octahydro-pyrrolo[3,4-b]pyridin-1-yl)-2-phenyl-oxazolo[5,4-d]pyrimidine | CHEMBL174158 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H25N5O |
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| Mol. Mass. | 411.4989 |
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| SMILES | C(N1C[C@@H]2CCCN([C@@H]2C1)c1ncnc2oc(nc12)-c1ccccc1)c1ccccc1 |
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| Structure | 
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