| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid scaffolding protein |
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| Ligand | BDBM50143621 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_77299 (CHEMBL687228) |
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| IC50 | 5.1±n/a nM |
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| Citation |  Gopalsamy, A; Lim, K; Ellingboe, JW; Mitsner, B; Nikitenko, A; Upeslacis, J; Mansour, TS; Olson, MW; Bebernitz, GA; Grinberg, D; Feld, B; Moy, FJ; O'Connell, J Design and syntheses of 1,6-naphthalene derivatives as selective HCMV protease inhibitors. J Med Chem47:1893-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid scaffolding protein |
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| Name: | Capsid scaffolding protein |
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| Synonyms: | APNG | Assemblin | Assembly protein | Capsid protein P40 | Human cytomegalovirus protease (HCMV Pr) | Human herpes virus 5 capsid protein P40 | Protease precursor | SCAF_HCMVA | UL80 | pPR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 73854.16 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_158958 |
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| Residue: | 708 |
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| Sequence: | MTMDEQQSQAVAPVYVGGFLARYDQSPDEAELLLPRDVVEHWLHAQGQGQPSLSVALPLN
INHDDTAVVGHVAAMQSVRDGLFCLGCVTSPRFLEIVRRASEKSELVSRGPVSPLQPDKV
VEFLSGSYAGLSLSSRRCDDVEAATSLSGSETTPFKHVALCSVGRRRGTLAVYGRDPEWV
TQRFPDLTAADRDGLRAQWQRCGSTAVDASGDPFRSDSYGLLGNSVDALYIRERLPKLRY
DKQLVGVTERESYVKASVSPEAACDIKAASAERSGDSRSQAATPAAGARVPSSSPSPPVE
PPSPVQPPALPASPSVLPAESPPSLSPSEPAEAASMSHPLSAAVPAATAPPGATVAGASP
AVSSLAWPHDGVYLPKDAFFSLLGASRSAVPVMYPGAVAAPPSASPAPLPLPSYPASYGA
PVVGYDQLAARHFADYVDPHYPGWGRRYEPAPSLHPSYPVPPPPSPAYYRRRDSPGGMDE
PPSGWERYDGGHRGQSQKQHRHGGSGGHNKRRKETAAASSSSSDEDLSFPGEAEHGRARK
RLKSHVNSDGGSGGHAGSNQQQQQRYDELRDAIHELKRDLFAARQSSTLLSAALPSAASS
SPTTTTVCTPTGELTSGGGETPTALLSGGAKVAERAQAGVVNASCRLATASGSEAATAGP
STAGSSSCPASVVLAAAAAQAAAASQSPPKDMVDLNRRIFVAALNKLE
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| BDBM50143621 |
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| n/a |
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| Name | BDBM50143621 |
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| Synonyms: | CHEMBL55390 | N-[5-(3-Chloro-benzyloxy)-naphthalen-2-yl]-terephthalamic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C25H18ClNO4 |
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| Mol. Mass. | 431.868 |
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| SMILES | OC(=O)c1ccc(cc1)C(=O)Nc1ccc2c(OCc3cccc(Cl)c3)cccc2c1 |
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| Structure | 
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