| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon receptor |
|---|
| Ligand | BDBM50144003 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_72991 |
|---|
| Ki | 51±n/a nM |
|---|
| Citation |  Kurukulasuriya, R; Sorensen, BK; Link, JT; Patel, JR; Jae, HS; Winn, MX; Rohde, JR; Grihalde, ND; Lin, CW; Ogiela, CA; Adler, AL; Collins, CA Biaryl amide glucagon receptor antagonists. Bioorg Med Chem Lett14:2047-50 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon receptor |
|---|
| Name: | Glucagon receptor |
|---|
| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 54026.92 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P47871 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
|
|
|
|---|
| BDBM50144003 |
|---|
| n/a |
|---|
| Name | BDBM50144003 |
|---|
| Synonyms: | 3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethoxy-phenylcarbamoyl)-ethyl]-benzoylamino}-propionic acid | CHEMBL62412 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H31F3N2O5 |
|---|
| Mol. Mass. | 556.5727 |
|---|
| SMILES | CC(C)(C)c1ccc(cc1)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
