| Reaction Details |
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 | Report a problem with these data |
| Target | Plasminogen |
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| Ligand | BDBM50144092 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_155584 |
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| IC50 | >10000±n/a nM |
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| Citation |  Jia, ZJ; Su, T; Zuckett, JF; Wu, Y; Goldman, EA; Li, W; Zhang, P; Clizbe, LA; Song, Y; Bauer, SM; Huang, W; Woolfrey, J; Sinha, U; Arfsten, AE; Hutchaleelaha, A; Hollenbach, SJ; Lambing, JL; Scarborough, RM; Zhu, BY N,N-Dialkylated 4-(4-arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((4-arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as potent factor Xa inhibitors. Bioorg Med Chem Lett14:2073-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Plasminogen |
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| Name: | Plasminogen |
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| Synonyms: | PLMN_RAT | Plasmin | Plasminogen | Plg |
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| Type: | Protein |
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| Mol. Mass.: | 90541.87 |
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| Organism: | Rattus norvegicus |
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| Description: | Q01177 |
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| Residue: | 812 |
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| Sequence: | MDHKEIILLFLLFLKPGQGDSLDGYVSTQGASLHSLTKKQLAAGSIADCLAKCEGETDFI
CRSFQYHSKEQQCVIMAENSKTSSIIRMRDVILFEKRVYLSECKTGIGKGYRGTMSKTKT
GVTCQKWSDTSPHVPKYSPSTHPSEGLEENYCRNPDNDEQGPWCYTTDPDQRYEYCNIPE
CEEECMYCSGEKYEGKISKTMSGLDCQSWDSQSPHAHGYIPAKFPSKNLKMNYCRNPDGE
PRPWCFTTDPNKRWEYCDIPRCTTPPPPPGPTYQCLKGRGENYRGTVSVTASGKTCQRWS
EQTPHRHNRTPENFPCKNLEENYCRNPDGETAPWCYTTDSQLRWEYCEIPSCGSSVSPDQ
SDSSVLPEQTPVVQECYQGNGKSYRGTSSTTNTGKKCQSWVSMTPHSHSKTPANFPDAGL
EMNYCRNPDNDQRGPWCFTTDPSVRWEYCNLKRCSETGGGVAESAIVPQVPSAPGTSETD
CMYGNGKEYRGKTAVTAAGTPCQEWAAQEPHSHRIFTPQTNPRAGLEKNYCRNPDGDVNG
PWCYTMNPRKLYDYCNIPLCASLSSFECGKPQVEPKKCPGRVVGGCVANPHSWPWQISLR
TRFSGQHFCGGTLISPEWVLTAAHCLEKSSRPEFYKVILGAHEERILGSDVQQIAVTKLV
LEPNDADIALLKLSRPATITDNVIPACLPSPNYVVADRTLCYITGWGETKGTPGAGRLKE
AQLPVIENKVCNRAEYLNNRVKSTELCAGHLAGGIDSCQGDSGGPLVCFEKDKYILQGVT
SWGLGCARPNKPGVYVRVSRYVNWIEREMRND
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| BDBM50144092 |
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| n/a |
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| Name | BDBM50144092 |
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| Synonyms: | CHEMBL294121 | [4-(5-Chloro-1H-indole-2-sulfonyl)-piperazin-1-yl]-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-phenyl]-methanone |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24ClN5O3S |
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| Mol. Mass. | 485.986 |
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| SMILES | CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1 |c:4| |
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| Structure | 
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