| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B2 |
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| Ligand | BDBM50144329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_206146 |
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| IC50 | 3300±n/a nM |
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| Citation |  Nantermet, PG; Barrow, JC; Lindsley, SR; Young, M; Mao, SS; Carroll, S; Bailey, C; Bosserman, M; Colussi, D; McMasters, DR; Vacca, JP; Selnick, HG Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P(1)(') group. Bioorg Med Chem Lett14:2141-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B2 |
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| Name: | Carboxypeptidase B2 |
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| Synonyms: | CBPB2_HUMAN | CPB2 | CPU | Carboxypeptidase B2 | Carboxypeptidase B2 isoform A | Carboxypeptidase U | Plasma carboxypeptidase B | TAFI | Thrombin-activable fibrinolysis inhibitor | pCPB |
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| Type: | Enzyme |
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| Mol. Mass.: | 48432.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96IY4 |
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| Residue: | 423 |
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| Sequence: | MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKISKNTRYTHGHGSE
TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
RNV
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| BDBM50144329 |
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| n/a |
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| Name | BDBM50144329 |
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| Synonyms: | 3-Imidazo[1,2-a]pyridin-6-yl-2-(1H-imidazol-4-yl)-propionic acid | CHEMBL67191 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12N4O2 |
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| Mol. Mass. | 256.26 |
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| SMILES | OC(=O)C(Cc1ccc2nccn2c1)c1cnc[nH]1 |
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| Structure | 
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