| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxypeptidase B |
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| Ligand | BDBM50144334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_45638 |
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| IC50 | 3700±n/a nM |
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| Citation |  Nantermet, PG; Barrow, JC; Lindsley, SR; Young, M; Mao, SS; Carroll, S; Bailey, C; Bosserman, M; Colussi, D; McMasters, DR; Vacca, JP; Selnick, HG Imidazole acetic acid TAFIa inhibitors: SAR studies centered around the basic P(1)(') group. Bioorg Med Chem Lett14:2141-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxypeptidase B |
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| Name: | Carboxypeptidase B |
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| Synonyms: | CBPB1_HUMAN | CPB | CPB1 | Carboxypeptidase B | PASP | PCPB | Pancreas-specific protein | Thrombin-activatable fibrinolysis (TAFI) |
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| Type: | Enzyme |
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| Mol. Mass.: | 47367.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15086 |
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| Residue: | 417 |
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| Sequence: | MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
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| BDBM50144334 |
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| n/a |
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| Name | BDBM50144334 |
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| Synonyms: | 6-Amino-2-(1H-imidazol-4-yl)-hexanoic acid | CHEMBL65910 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H15N3O2 |
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| Mol. Mass. | 197.2343 |
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| SMILES | NCCCCC(C(O)=O)c1cnc[nH]1 |
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| Structure | 
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