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TargetKallikrein-1
LigandBDBM50147084
Substrate/Competitorn/a
Meas. Tech.ChEBML_148015
Ki 400±n/a nM
Citation Wendt, MDGeyer, AMcClellan, WJRockway, TWWeitzberg, MZhao, XMantei, RStewart, KNienaber, VKlinghofer, VGiranda, VL Interaction with the S1 beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg Med Chem Lett14:3063-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Kallikrein-1
Name:Kallikrein-1
Synonyms:KLK1 | KLK1_HUMAN | Kallikrein 1 | Kallikrein-1 | Kidney/pancreas/salivary gland kallikrein | Tissue kallikrein
Type:Enzyme
Mol. Mass.:28874.69
Organism:Homo sapiens (Human)
Description:P06870
Residue:262
Sequence:
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
PSVAVRVLSYVKWIEDTIAENS
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  Blast E-value cutoff:
BDBM50147084
n/a
NameBDBM50147084
Synonyms:6-Carbamimidoyl-4-(tetrahydro-furan-3-yl)-naphthalene-2-carboxylic acid phenylamide | 6-carbamimidoyl-N-phenyl-4-(tetrahydrofuran-3-yl)-2-naphthamide | CHEMBL105395
TypeSmall organic molecule
Emp. Form.C22H21N3O2
Mol. Mass.359.421
SMILESNC(=N)c1ccc2cc(cc(C3CCOC3)c2c1)C(=O)Nc1ccccc1
Structure
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