| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dynamin-1 |
|---|
| Ligand | BDBM50147572 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_60874 |
|---|
| IC50 | 8850.0±n/a nM |
|---|
| Citation |  Hill, TA; Odell, LR; Quan, A; Abagyan, R; Ferguson, G; Robinson, PJ; McCluskey, A Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorg Med Chem Lett14:3275-8 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dynamin-1 |
|---|
| Name: | Dynamin-1 |
|---|
| Synonyms: | DNM | DNM1 | DYN1_HUMAN | Dynamin-1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 97411.67 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1458576 |
|---|
| Residue: | 864 |
|---|
| Sequence: | MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI
REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
PGVPSRSGQASPSRPESPRPPFDL
|
|
|
|---|
| BDBM50147572 |
|---|
| n/a |
|---|
| Name | BDBM50147572 |
|---|
| Synonyms: | CHEMBL321384 | Tridecanoic acid (2-dimethylamino-ethyl)-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H36N2O |
|---|
| Mol. Mass. | 284.4805 |
|---|
| SMILES | CCCCCCCCCCCCC(=O)NCCN(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
