| Reaction Details |
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 | Report a problem with these data |
| Target | Dynamin-1 |
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| Ligand | BDBM50147577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_60874 |
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| IC50 | 8450.0±n/a nM |
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| Citation |  Hill, TA; Odell, LR; Quan, A; Abagyan, R; Ferguson, G; Robinson, PJ; McCluskey, A Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorg Med Chem Lett14:3275-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dynamin-1 |
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| Name: | Dynamin-1 |
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| Synonyms: | DNM | DNM1 | DYN1_HUMAN | Dynamin-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 97411.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458576 |
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| Residue: | 864 |
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| Sequence: | MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI
REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
PGVPSRSGQASPSRPESPRPPFDL
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| BDBM50147577 |
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| n/a |
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| Name | BDBM50147577 |
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| Synonyms: | CHEMBL109914 | Triethyl-tetradecyl-ammonium; bromide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H44N |
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| Mol. Mass. | 298.5695 |
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| SMILES | CCCCCCCCCCCCCC[N+](CC)(CC)CC |
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| Structure | 
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