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TargetSphingosine 1-phosphate receptor 4
LigandBDBM50147701
Substrate/Competitorn/a
Meas. Tech.ChEMBL_201335 (CHEMBL806184)
IC50>10000±n/a nM
Citation Hale, JJNeway, WMills, SGHajdu, RAnn Keohane, CRosenbach, MMilligan, JShei, GJChrebet, GBergstrom, JCard, DKoo, GCKoprak, SLJackson, JJRosen, HMandala, S Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720. Bioorg Med Chem Lett14:3351-5 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 4
Name:Sphingosine 1-phosphate receptor 4
Synonyms:EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41647.39
Organism:Homo sapiens (Human)
Description:n/a
Residue:384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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  Blast E-value cutoff:
BDBM50147701
n/a
NameBDBM50147701
Synonyms:4-Amino-6-(4-octyl-phenyl)-hexanoic acid | 4-amino-6-(4-octylphenyl)hexanoic acid | CHEMBL325050
TypeSmall organic molecule
Emp. Form.C20H33NO2
Mol. Mass.319.4815
SMILESCCCCCCCCc1ccc(CCC(N)CCC(O)=O)cc1
Structure
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