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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mu-type opioid receptor | ||
| Ligand | BDBM50147745 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_148097 (CHEMBL751579) | ||
| Ki | 22±n/a nM | ||
| Citation |  Zaveri, NT; Jiang, F; Olsen, CM; Deschamps, JR; Parrish, D; Polgar, W; Toll, L A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor. J Med Chem47:2973-6 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mu-type opioid receptor | |||
| Name: | Mu-type opioid receptor | ||
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 44789.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35372 | ||
| Residue: | 400 | ||
| Sequence: |
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| BDBM50147745 | |||
| n/a | |||
| Name | BDBM50147745 | ||
| Synonyms: | 1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-1,3-dihydro-indol-2-one | CHEMBL99738 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H32N2O | ||
| Mol. Mass. | 340.5023 | ||
| SMILES | CC(C)[C@H]1CC[C@@H](CC1)N1CCC(CC1)N1C(=O)Cc2ccccc12 |wU:3.2,wD:6.9,(24.92,-3.48,;24.12,-2.15,;24.85,-.8,;22.58,-2.2,;21.84,-3.55,;20.3,-3.58,;19.5,-2.27,;20.23,-.92,;21.77,-.87,;17.97,-2.31,;17.15,-.99,;15.61,-1.03,;14.89,-2.39,;15.7,-3.71,;17.22,-3.66,;13.35,-2.43,;12.41,-1.22,;12.84,.26,;10.96,-1.73,;11.01,-3.27,;9.9,-4.34,;10.27,-5.84,;11.74,-6.26,;12.86,-5.2,;12.49,-3.69,)| | ||
| Structure | 
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