| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50148310 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_45556 |
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| IC50 | 0.130000±n/a nM |
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| Citation |  Boros, EE; Deaton, DN; Hassell, AM; McFadyen, RB; Miller, AB; Miller, LR; Paulick, MG; Shewchuk, LM; Thompson, JB; Willard, DH; Wright, LL Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors. Bioorg Med Chem Lett14:3425-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM50148310 |
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| n/a |
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| Name | BDBM50148310 |
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| Synonyms: | ((S)-1-Formyl-pentyl)-carbamic acid (S)-1-benzyl-propyl ester | CHEMBL114462 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H25NO3 |
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| Mol. Mass. | 291.3853 |
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| SMILES | CCCC[C@H](NC(=O)O[C@@H](CC)Cc1ccccc1)C=O |
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| Structure | 
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