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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Beta-lactamase | ||
| Ligand | BDBM50053173 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_41203 (CHEMBL652839) | ||
| IC50 | 84000±0 nM | ||
| Citation |  Tabei, K; Feng, X; Venkatesan, AM; Abe, T; Hideki, U; Mansour, TS; Siegel, MM Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry. J Med Chem47:3674-88 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Beta-lactamase | |||
| Name: | Beta-lactamase | ||
| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC | ||
| Type: | Protien | ||
| Mol. Mass.: | 41561.62 | ||
| Organism: | Escherichia coli | ||
| Description: | P00811 | ||
| Residue: | 377 | ||
| Sequence: |
| ||
| BDBM50053173 | |||
| n/a | |||
| Name | BDBM50053173 | ||
| Synonyms: | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda 6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide | 3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid | CHEMBL404 | CL-298741 | TAZOBACTAM | US9120808, Tazobactam sodium salt | US9676777, TAZ | YTR-830H | Zosyn | ||
| Type | Small organic molecule | ||
| Emp. Form. | C10H12N4O5S | ||
| Mol. Mass. | 300.291 | ||
| SMILES | C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(O)=O |r| | ||
| Structure | 
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