| Reaction Details |
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 | Report a problem with these data |
| Target | 17beta-hydroxysteroid dehydrogenase |
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| Ligand | BDBM50149603 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306373 (CHEMBL828344) |
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| IC50 | 5000±n/a nM |
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| Citation |  Gobec, S; Sova, M; Kristan, K; Rizner, TL Cinnamic acid esters as potent inhibitors of fungal 17beta-hydroxysteroid dehydrogenase--a model enzyme of the short-chain dehydrogenase/reductase superfamily. Bioorg Med Chem Lett14:3933-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 17beta-hydroxysteroid dehydrogenase |
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| Name: | 17beta-hydroxysteroid dehydrogenase |
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| Synonyms: | 17-beta-hydroxysteroid-dehydrogenase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28901.23 |
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| Organism: | Curvularia lunata |
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| Description: | ChEMBL_306373 |
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| Residue: | 270 |
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| Sequence: | MPHVENASETYIPGRLDGKVALVTGSGRGIGAAVAVHLGRLGAKVVVNYANSTKDAEKVV
SEIKALGSDAIAIKADIRQVPEIVKLFDQAVAHFGHLDIAVSNSGVVSFGHLKDVTEEEF
DRVFSLNTRGQFFVAREAYRHLTEGGRIVLTSSNTSKDFSVPKHSLYSGSKGAVDSFVRI
FSKDCGDKKITVNAVAPGGTVTDMFHEVSHHYIPNGTSYTAEQRQQMAAHASPLHRNGWP
QDVANVVGFLVSKEGEWVNGKVLTLDGGAA
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| BDBM50149603 |
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| n/a |
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| Name | BDBM50149603 |
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| Synonyms: | (E)-3-Phenyl-acrylic acid 2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester | CHEMBL363306 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15NO4 |
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| Mol. Mass. | 321.3267 |
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| SMILES | O=C(OCCN1C(=O)c2ccccc2C1=O)\C=C\c1ccccc1 |
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| Structure | 
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