| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM50149784 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_302784 (CHEMBL839469) |
|---|
| Ki | 450±n/a nM |
|---|
| Citation |  Buzzoni, V; Blazquez, J; Ferrari, S; Calò, S; Venturelli, A; Costi, MP Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase. Bioorg Med Chem Lett14:3979-83 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
|---|
| Type: | Protien |
|---|
| Mol. Mass.: | 41561.62 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P00811 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
|
|
|
|---|
| BDBM50149784 |
|---|
| n/a |
|---|
| Name | BDBM50149784 |
|---|
| Synonyms: | Aza-boronic acid derivative | CHEMBL180679 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H13BN2O4 |
|---|
| Mol. Mass. | 308.096 |
|---|
| SMILES | OB(O)c1cccc(c1)N=Nc1c(O)cc(O)c2ccccc12 |w:9.9| |
|---|
| Structure | 
|
|---|
Search and Browse
