Reaction Details |
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Target | Gag-Pol polyprotein [489-587] |
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Ligand | BDBM50150028 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_302271 (CHEMBL830291) |
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Ki | 0.01±n/a nM |
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Citation | Huang, PP; Randolph, JT; Klein, LL; Vasavanonda, S; Dekhtyar, T; Stoll, VS; Kempf, DJ Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors. Bioorg Med Chem Lett14:4075-8 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Gag-Pol polyprotein [489-587] |
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Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50150028 |
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n/a |
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Name | BDBM50150028 |
Synonyms: | (5R,6R)-1-Benzoyl-5-benzyl-6-hydroxy-2,4-bis-(4-hydroxy-benzyl)-[1,2,4]triazepan-3-one | CHEMBL182611 |
Type | Small organic molecule |
Emp. Form. | C32H31N3O5 |
Mol. Mass. | 537.6056 |
SMILES | O[C@@H]1CN(N(Cc2ccc(O)cc2)C(=O)N(Cc2ccc(O)cc2)[C@@H]1Cc1ccccc1)C(=O)c1ccccc1 |
Structure |
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