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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM192
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302271
Ki 0.07±n/a nM
Citation Huang PPRandolph JTKlein LLVasavanonda SDekhtyar TStoll VSKempf DJ Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors. Bioorg Med Chem Lett 14:4075-8 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM192
n/a
NameBDBM192
Synonyms:(5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxyphenyl)methyl]-1,2,4-triazepan-3-one | (5R,6R)-2,4-Bis(4-hydroxybenzyl)-1,5-dibenzyl-6-hydroxy-3-oxo-1,2,4-triazacycloheptane | CHEMBL130078 | Unnamed azacyclic urea
Typen/a
Emp. Form.C32H33N3O4
Mol. Mass.523.6221
SMILESO[C@@H]1CN(Cc2ccccc2)N(Cc2ccc(O)cc2)C(=O)N(Cc2ccc(O)cc2)[C@@H]1Cc1ccccc1 |r|
Structure
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