| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM50150406 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302553 (CHEMBL828254) |
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| Ki | 9±n/a nM |
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| Citation |  Mattson, RJ; Denhart, DJ; Catt, JD; Dee, MF; Deskus, JA; Ditta, JL; Epperson, J; Dalton King, H; Gao, A; Poss, MA; Purandare, A; Tortolani, D; Zhao, Y; Yang, H; Yeola, S; Palmer, J; Torrente, J; Stark, A; Johnson, G Aminotriazine 5-HT7 antagonists. Bioorg Med Chem Lett14:4245-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 53573.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34969 |
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| Residue: | 479 |
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| Sequence: | MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTW
DAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLI
VSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDR
YLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYT
IYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVE
ECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSC
IPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALK
LAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
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| BDBM50150406 |
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| n/a |
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| Name | BDBM50150406 |
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| Synonyms: | CHEMBL182418 | N-[(S)-1-(4-Fluoro-phenyl)-ethyl]-N''-(2-pyridin-2-yl-ethyl)-[1,3,5]triazine-2,4,6-triamine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20FN7 |
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| Mol. Mass. | 353.3967 |
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| SMILES | C[C@H](Nc1nc(N)nc(NCCc2ccccn2)n1)c1ccc(F)cc1 |
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| Structure | 
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