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Target5-hydroxytryptamine receptor 2C
LigandBDBM50150431
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302566 (CHEMBL839528)
Ki 15±n/a nM
Citation Denhart, DJ; Purandare, AV; Catt, JD; King, HD; Gao, A; Deskus, JA; Poss, MA; Stark, AD; Torrente, JR; Johnson, G; Mattson, RJ Diaminopyrimidine and diaminopyridine 5-HT7 ligands. Bioorg Med Chem Lett14:4249-52 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 2C
Name:5-hydroxytryptamine receptor 2C
Synonyms:5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51836.79
Organism:Homo sapiens (Human)
Description:P28335
Residue:458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50150431
n/a
NameBDBM50150431
Synonyms:(S)-N2-(2-(4-fluorophenoxy)ethyl)-N4-(1-phenylethyl)pyridine-2,4-diamine | CHEMBL363452 | N*2*-[2-(4-Fluoro-phenoxy)-ethyl]-N*4*-((S)-1-phenyl-ethyl)-pyridine-2,4-diamine
TypeSmall organic molecule
Emp. Form.C21H22FN3O
Mol. Mass.351.4173
SMILESC[C@H](Nc1ccnc(NCCOc2ccc(F)cc2)c1)c1ccccc1
Structure
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