| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
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| Ligand | BDBM50150833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303300 (CHEMBL827433) |
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| Ki | 21±n/a nM |
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| Citation |  Chen, C; Yu, J; Fleck, BA; Hoare, SR; Saunders, J; Foster, AC Phenylguanidines as selective nonpeptide melanocortin-5 receptor antagonists. J Med Chem47:4083-8 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 5 |
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| Name: | Melanocortin receptor 5 |
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| Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36612.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P33032 |
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| Residue: | 325 |
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| Sequence: | MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
EMRKTFKEIICCRGFRIACSFPRRD
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| BDBM50150833 |
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| n/a |
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| Name | BDBM50150833 |
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| Synonyms: | 4-[((S)-N-Cyclohexyl-3-methyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide | CHEMBL185455 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H35Cl2N5O |
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| Mol. Mass. | 516.506 |
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| SMILES | C[C@H]1CN(CCN1)C(Nc1ccc(cc1)C(=O)NCCc1ccc(Cl)cc1Cl)=NC1CCCCC1 |w:28.31| |
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| Structure | 
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