| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50151503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302995 (CHEMBL830234) |
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| Ki | 36000±n/a nM |
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| Citation |  Mutulis, F; Yahorava, S; Mutule, I; Yahorau, A; Liepinsh, E; Kopantshuk, S; Veiksina, S; Tars, K; Belyakov, S; Mishnev, A; Rinken, A; Wikberg, JE New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of"THIQ". J Med Chem47:4613-26 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34717.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q01726 |
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| Residue: | 317 |
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| Sequence: | MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
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| BDBM50151503 |
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| n/a |
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| Name | BDBM50151503 |
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| Synonyms: | 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid [(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-oxy-4-phenyl-piperazin-1-yl)-ethyl]-amide | CHEMBL362010 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31ClN4O3 |
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| Mol. Mass. | 519.034 |
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| SMILES | [O-][N+]1(CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)C1Cc2ccccc2CN1)c1ccccc1 |
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| Structure | 
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