| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor beta |
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| Ligand | BDBM50152609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305919 (CHEMBL832634) |
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| IC50 | 0.35±n/a nM |
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| Citation |  Collini, MD; Kaufman, DH; Manas, ES; Harris, HA; Henderson, RA; Xu, ZB; Unwalla, RJ; Miller, CP 7-Substituted 2-phenyl-benzofurans as ER beta selective ligands. Bioorg Med Chem Lett14:4925-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen receptor beta |
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| Name: | Estrogen receptor beta |
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| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta |
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| Type: | Protein |
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| Mol. Mass.: | 59238.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q92731 |
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| Residue: | 530 |
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| Sequence: | MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
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| BDBM50152609 |
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| n/a |
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| Name | BDBM50152609 |
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| Synonyms: | 7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzofuran-5-ol | CHEMBL182850 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H8BrFO3 |
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| Mol. Mass. | 323.114 |
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| SMILES | Oc1cc(Br)c2oc(cc2c1)-c1ccc(O)c(F)c1 |
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| Structure | 
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