| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V2 receptor |
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| Ligand | BDBM50152974 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304151 (CHEMBL828131) |
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| EC50 | 850±n/a nM |
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| Citation |  Pitt, GR; Batt, AR; Haigh, RM; Penson, AM; Robson, PA; Rooker, DP; Tartar, AL; Trim, JE; Yea, CM; Roe, MB Non-peptide oxytocin agonists. Bioorg Med Chem Lett14:4585-9 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V2 receptor |
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| Name: | Vasopressin V2 receptor |
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| Synonyms: | ADHR | AVPR V2 | AVPR2 | Antidiuretic hormone receptor | DIR | DIR3 | Renal-type arginine vasopressin receptor | V2R | V2R_HUMAN | VASOPRESSIN V2 | Vasopressin V2 receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 40295.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30518 |
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| Residue: | 371 |
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| Sequence: | MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA
ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM
VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ
RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP
SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA
PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT
ASSSLAKDTSS
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| BDBM50152974 |
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| n/a |
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| Name | BDBM50152974 |
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| Synonyms: | (2S)-N-{2-Methyl-4-[(1-methyl-4,10-dihydropyrazolo[3,4-b]-[1,5]benzodiazepin-5(1H)-yl)carbonyl]benzyl}-2-[(4-methyl-1,4-diazepan-1-yl)carbonothioyl]pyrrolidine-1-carboxamide | (S)-2-(4-Methyl-[1,4]diazepane-1-carbothioyl)-pyrrolidine-1-carboxylic acid 2-methyl-4-(3-methyl-4,10-dihydro-3H-2,3,4,9-tetraaza-benzo[f]azulene-9-carbonyl)-benzylamide | CHEMBL360648 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N8O2S |
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| Mol. Mass. | 600.777 |
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| SMILES | CN1CCCN(CC1)C(=S)[C@@H]1CCCN1C(=O)NCc1ccc(cc1C)C(=O)N1Cc2cnn(C)c2Nc2ccccc12 |
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| Structure | 
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