| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5A, mitochondrial |
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| Ligand | BDBM50155503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305668 (CHEMBL827937) |
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| IC50 | 44900.0±n/a nM |
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| Citation |  Innocenti, A; Antel, J; Wurl, M; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. Bioorg Med Chem Lett14:5703-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5A, mitochondrial |
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| Name: | Carbonic anhydrase 5A, mitochondrial |
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| Synonyms: | CA-VA | CA5 | CA5A | CAH5A_HUMAN | Carbonate dehydratase VA | Carbonic Anhydrase VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase 5A, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VA (CA VA) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34755.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 305 |
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| Sequence: | MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPG
GTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPL
ENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVI
GVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLT
ESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATN
EGTRS
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| BDBM50155503 |
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| n/a |
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| Name | BDBM50155503 |
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| Synonyms: | 6-Nitro-benzothiazole-2-sulfonic acid amide | CHEMBL186335 |
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| Type | Small organic molecule |
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| Emp. Form. | C7H5N3O4S2 |
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| Mol. Mass. | 259.262 |
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| SMILES | NS(=O)(=O)c1nc2ccc(cc2s1)[N+]([O-])=O |
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| Structure | 
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