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TargetGag-Pol polyprotein [489-587]
LigandBDBM50155991
Substrate/Competitorn/a
Meas. Tech.ChEMBL_303547 (CHEMBL839752)
Ki 0.600000±n/a nM
Citation Huang, DCaflisch, A Efficient evaluation of binding free energy using continuum electrostatics solvation. J Med Chem47:5791-7 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50155991
n/a
NameBDBM50155991
Synonyms:2-{2-[(2R,4S)-5-(2-Benzyloxycarbonylamino-propionylamino)-4-hydroxy-6-phenyl-2-propyl-hexanoylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid methyl ester | CHEMBL363028
TypeSmall organic molecule
Emp. Form.C37H54N4O8
Mol. Mass.682.8467
SMILESCCC[C@H](C[C@H](O)C(Cc1ccccc1)NC(=O)C(C)NC(=O)OCc1ccccc1)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)OC
Structure
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