| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
|---|
| Ligand | BDBM50156256 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303403 (CHEMBL839160) |
|---|
| EC50 | 0.280000±n/a nM |
|---|
| Citation |  Mizuno, K; Sawa, M; Harada, H; Tateishi, H; Oue, M; Tsujiuchi, H; Furutani, Y; Kato, S Tryptamine-based human beta3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring. Bioorg Med Chem Lett14:5959-62 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-3 adrenergic receptor |
|---|
| Name: | Beta-3 adrenergic receptor |
|---|
| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43534.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 408 |
|---|
| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
|
|
|
|---|
| BDBM50156256 |
|---|
| n/a |
|---|
| Name | BDBM50156256 |
|---|
| Synonyms: | CHEMBL186135 | Octane-1-sulfonic acid 3-(2-{(R)-(R)-2-hydroxy-2-[3-(thiophene-2-sulfonylamino)-phenyl]-ethylamino}-propyl)-1H-indol-7-yl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H41N3O6S3 |
|---|
| Mol. Mass. | 647.869 |
|---|
| SMILES | CCCCCCCCS(=O)(=O)Oc1cccc2c(C[C@@H](C)NC[C@H](O)c3cccc(NS(=O)(=O)c4cccs4)c3)c[nH]c12 |
|---|
| Structure | 
|
|---|
Search and Browse
